Sesquiterpene lactones have attracted much attention in drug research because they
present a series of biological activities such as anticancer, antifungal, anti-inflammatory,
antimicrobial and antioxidant. Leptocarpin (LTC) is a sesquiterpene lactone isolated from a
native Chilean plant, Leptocarpha rivularis, which has been widely used in traditional
medicine by Mapuche people. Previous work has demonstrated that LTC decreases cell
viability of cancer cell lines. In this contribution, we analyze the mechanism of LTC …