… 25(OH)D concentrations <140 nmol/L, which require a total … D supply of 250 μg (10000
IU)/d to attain. Published cases of vitamin D toxicity with hypercalcemia, for which the 25(OH)D …

… liver on carbon 25 to form 25-hydroxyvitamin D [25(OH)D], and then in the kidney for a … D,
1,25-dihydroxyvitamin D [1,25(OH) 2 D]. With the identification of 25(OH)D and 1,25(OH) 2 D, …

… Because the VDR is functional when exogenous 1,25(OH) 2 D 3 is added, we hypothesized
that the TLR2/1 induction of Cyp27B1 and the conversion of 25(OH)D 3 to 1,25(OH) 2 D 3 …

… In this article, I will discuss vitamin D metabolism, calcium homeostasis, the effects of vitamin
D on bone, genomic and non-genomic effects of vitamin D and finally extraskeletal effects …

… 1,25(OH) 2 D. 1,25(OH) 2 D and its analogs have been developed for treating the
hyperproliferative disease psoriasis. Vitamin D deficiency is a major unrecognized health problem. …

… D status in different regions of the world with the objective of understanding the scope of
hypovitaminosis D and … The purpose of this review is to provide a global perspective of vitamin D …

… to sunlight, which enhances the production of vitamin D 3 in the skin, is important in preventing
… D, sunlight supplies most of our vitamin D requirement. 25-Hydroxyvitamin D [25(OH)D] is …

… Determinants of circulating 25-hydroxyvitamin D … affecting vitamin D concentrations and
risk of insufficiency. … We undertook a genome-wide association study of 25-hydroxyvitamin D …

… D deficiency is a major risk factor for bone loss and fracture. Although hypovitaminosis D
has been detected frequently in elderly and housebound people, the prevalence of vitamin D …

… d for life-stage groups at least 1 yr of age. For vitamin D, RDAs of 600 IU/d for ages 1–70 yr
and 800 IU/d for ages 71 yr and older, corresponding to a serum 25-hydroxyvitamin D level of …