Deep learning for end-to-end atrial fibrillation recurrence estimation

R Bhalodia, A Goparaju, T Sodergren… - 2018 Computing in …, 2018 - ieeexplore.ieee.org
R Bhalodia, A Goparaju, T Sodergren, A Morris, E Kholmovski, N Marrouche, J Cates…
2018 Computing in Cardiology Conference (CinC), 2018ieeexplore.ieee.org
Left atrium shape has been shown to be an independent predictor of recurrence after atrial
fibrillation (AF) ablation. Shape-based representation is imperative to such an estimation
process, where correspondence-based representation offers the most flexibility and ease-of-
computation for population-level shape statistics. Nonetheless, population-level shape
representations in the form of image segmentation and correspondence models derived
from cardiac MRI require significant human resources with sufficient anatomy-specific …
Left atrium shape has been shown to be an independent predictor of recurrence after atrial fibrillation (AF) ablation. Shape-based representation is imperative to such an estimation process, where correspondence-based representation offers the most flexibility and ease-of-computation for population-level shape statistics. Nonetheless, population-level shape representations in the form of image segmentation and correspondence models derived from cardiac MRI require significant human resources with sufficient anatomy-specific expertise. In this paper, we propose a machine learning approach that uses deep networks to estimate AF recurrence by predicting shape descriptors directly from MRI images, with NO image pre-processing involved. We also propose a novel data augmentation scheme to effectively train a deep network in a limited training data setting. We compare this new method of estimating shape descriptors from images with the state-of-the-art correspondence-based shape modeling that requires image segmentation and correspondence optimization. Results show that the proposed method and the current state-of-the-art produce statistically similar outcomes on AF recurrence, eliminating the need for expensive pre-processing pipelines and associated human labor.
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