Neuroimaging studies have suggested the presence of alterations in the anatomo-functional
properties of the brain of patients with chronic pain. However, investigation of the brain
circuitry supporting the perception of clinical pain presents significant challenges,
particularly when using traditional neuroimaging approaches. While potential neuroimaging
markers for clinical pain have included resting brain connectivity, these cross-sectional
studies have not examined sensitivity to within-subject exacerbation of pain. We used the …