Signaling lymphocytic activation molecule (SLAM) family receptors (SFRs) can mediate
either activating or inhibitory effects during natural killer cell (NK cell) activation. In this study,
we addressed the global role, regulation, and mechanism of action of the SLAM family in NK
cells by analyzing a mouse lacking the entire∼ 400-kilobase Slam locus, which encodes all
six SFRs and CD48, the ligand of SFR 2B4. This mouse displayed enhanced NK cell
activation responses toward hematopoietic target cells. Analyses of mice lacking individual …

The authors regret that in the original online article, the contour plots in Fig. 10 F were not
correct. The plots in panel J were inadvertently copied to panel F during the revision
process. The contour plots in panel F have since been replaced in the online HTML and
PDF versions of the article as well as in the print version. The change does not alter the
conclusions of the paper.