Dengue haemorrhagic fever in adults: a prospective study of 110 cases

JP Wali, A Biswas, R Handa, P Aggarwal… - Tropical …, 1999 - journals.sagepub.com
JP Wali, A Biswas, R Handa, P Aggarwal, N Wig, SN Dwivedi
Tropical doctor, 1999journals.sagepub.com
One hundred and ten adult patients hospitalized with dengue haemorrhagic fever (DHF)
during the recent outbreak in North India were prospectively studied. Of these, 48 (43.6%)
were grade 1, 40 (36.4%) grade II, 10 (9.1%) grade III and 12 (10.9%) grade IV DHF.
Dengue shock syndrome (DSS) was seen in 22 (20%) patients. Fever, headache, myalgias
and arthralgias were the common symptoms seen in 100%, 80.9%, 76.2% and 52.3%
patients, respectively. Spontaneous bleeding was seen in 62 patients (56.4%) with …
One hundred and ten adult patients hospitalized with dengue haemorrhagic fever (DHF) during the recent outbreak in North India were prospectively studied. Of these, 48 (43.6%) were grade 1, 40 (36.4%) grade II, 10 (9.1%) grade III and 12 (10.9%) grade IV DHF. Dengue shock syndrome (DSS) was seen in 22 (20%) patients. Fever, headache, myalgias and arthralgias were the common symptoms seen in 100%, 80.9%, 76.2% and 52.3% patients, respectively. Spontaneous bleeding was seen in 62 patients (56.4%) with mucocutaneous bleeding being the most common (46 patients). Gastrointestinal bleeding was seen in 38 (34.5%) patients. In as many as 40 patients, the haemorrhagic manifestations occurred after the fever had come down. Fifty-five patients (50%) required platelet transfusions. Twelve patients died, giving a mortality rate of 10.9% in the present study. Prompt recognition and supportive treatment can be lifesaving.
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