Study Objectives: We sought to evaluate the relationship between osmolal gap and serum
ethanol level and derive a formula that can be used clinically to calculate the expected
osmolal gap in the presence of ethanol. Some investigators have noted that the residual
osmolal gap appears to increase as the ethanol level increases, and thus it is important to
determine the exact relationship between these 2 values. Methods: In part 1, a convenience
sample of emergency department patients undergoing serum ethanol determination had …