In modern scientific soil-less cultivation, aquaponics/integrated agri-aquaculture farming (IAAF) is gaining wide popularity, especially in urban and hilly areas with water and space constraints. Following the concept “waste to wealth,” this hi-tech natural/organic by-product utilization strategy produces fish and plants for human consumption and use without any external input. It requires only 10% of water as compared to the traditional farming. The recirculatory aquaponic system (RAS) has the benefit of solving problems like waste management headaches and unwanted weed infestation, including soil-borne pests and diseases, hence, providing optimum space for the growth of much healthier plants. In an optimized system, the fish, plant, and microbial (bio-filter) components technically co-exist in symbiotic equilibrium, where the ammonia- and nitrite-oxidizing bacteria convert the toxic ammonia to nitrate for utilization by plants. However, some proportions of nitrite and ammonia are also utilized by the plants, depending on their species and varieties. The varieties with hardy nature and giving better production are chosen. Selection of fish and plant species varies according to the type, locality, and aquaponics method for the grow-out cultivation. Based on the material compatibility and type of plants to be cultivated, several categories of organic and inorganic media bed substrates can be used to cater the needs. are a good number of aquaponic techniques such as nutrient film technique (NFT), media bed, deep water culture (DWC)/raft, drip and wick system, Verti Stack, Dutch bucket, Vertigrow, ebb and flow (flood and drain), aeroponics, etc. are practiced in small scale to commercial farming, each bearing its benefits. These systems can be installed in the form of mini, small, semi, hobby, open pond, domestic, backyard, demonstration, or commercial way as per their purpose, area confinement, and scale of operation. As a primary food source, aquaponics may not fully replace the long-established conventional farming. Still, it can suffice as a much-warranted solution for the area/country without possessing adequate space, water, and fertile soil for the fisheries and agriculture to promote further.