In recent times there are many modern advancements came in the area of fixture design and assembly. In this paper attempt has been made to design and analyze the modern screw less machine vice using CATIA and ANSYS APDL package. The drawbacks of existing vice were overcome by new screw less machine vice. In the existing system of machine vice the lead screw will tend to undergo frequent wear and tear due to abrasion resistance problem as a result jaw of vice lose its grip to hold the work component. In order to overcome such type of problem dowel pin type movable jaw was designed in such a way in order to incorporate into the base block of movable jaw.