The rear-view mirror (RVM) of a Maruti Suzuki RITZ car was modeled using the reverse engineering (RE) and further the design of RVM is modified using CATIA. A Computational fluid dynamics (CFD) model was built to investigate the wake structure and the vortex body frame interaction near the unmodified and modified RVM of a car. The velocity vector fields in the wake and pressure distribution over the RVM skin were measured at Reynolds number of 2.6× 105 using ANSYS fluent software. The results of CFD model for unmodified and modified RVM designs are compared and consequently, the accuracy of the CFD analysis is validated from the manual calculation. The validation of CFD model was ensured by the experimentation using an open circuit blow down type wind tunnel. Once, the CFD model was validated, the design alterations are applied to the geometry of RVM with an aim of drag reduction. The CFD analysis of feasible RVM design modification reported a maximum of 45.7% drag reduction at a velocity of 108 km/h.