Development and efficient 1-glycyl-3-methyl imidazolium chloride–copper (II) complex catalyzed highly enantioselective synthesis of 3, 4-dihydropyrimidin-2 (1H) …

P Karthikeyan, SA Aswar, PN Muskawar… - Journal of …, 2013 - Elsevier
A novel, effective asymmetric 1-glycyl-3-methyl imidazolium chloride-copper (II) complex
[[Gmim] Cl–Cu (II)] was synthesized and studied as organocatalyst for enantioselective
Biginelli reaction under solvent free condition at 25° C. The hydrophobic group on amino
acid favors reagent diffusion towards the chloroglycine moiety increasing the catalytic
activity of supported palladium complex. Spectroscopic evidence of complex has been
proved by Powder XRD, SEM, FT-IR and AFM. This method contains simplified product …
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