Development and validation of new spectroscopic method for the estimation of furazolidone in bulk and solid dosage form

DS Mittan, P Kumar, SPV Prasad… - Oriental Journal of …, 2008 - search.proquest.com
DS Mittan, P Kumar, SPV Prasad, L Kumar, S Kumar
Oriental Journal of Chemistry, 2008search.proquest.com
A simple and sensitive spectroscopic method in ultraviolet region was developed and
validated for the estimation of Furazolidone in pure and pharmaceutical dosage forms. The
method is based on Furazolidone, showing absorbance at 259 nm for zero order derivative
spectroscopy respectively in acetonitrile and distilled water. This method obey's Beers law in
the concentration range of 2 to 18 ug/ml respectively. The proposed method is precise,
accurate, linear, stable and reproducible and can be extended to the analysis of …
Abstract
A simple and sensitive spectroscopic method in ultraviolet region was developed and validated for the estimation of Furazolidone in pure and pharmaceutical dosage forms. The method is based on Furazolidone, showing absorbance at 259 nm for zero order derivative spectroscopy respectively in acetonitrile and distilled water. This method obey’s Beers law in the concentration range of 2 to 18 ug/ml respectively. The proposed method is precise, accurate, linear, stable and reproducible and can be extended to the analysis of furazolidone in bulk and tablet formulations.
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