A new format for the microtiter plate-based assays was proposed. The novelty involves the
use of disk-shaped inserts for immobilization of biological and chemical reagents. The
internal opening of the disks allows measurements of the reactions by standard microtiter
plate readers without any additional steps involving liquid handling. Ideally the plate end-
users just have to add the sample and take the measurement without any need of multiple
reagent additions or transfer of the liquid to a different plate. The novel assay format also …