… SARS-CoV 3CL pro plays an important role in viral replication. In this study, we performed a
… on nine phlorotannins isolated from the edible brown algae Ecklonia cava. The nine isolated …

… also expressed significant potential as inhibitors. Finally, the … IPA, Dieckol, Eckmaxol, and
DPHC as inhibitors of SARS-CoV-2… Brown algae Ishige okamurae (IO) and Ecklonia cava (EC) …

… , Dieckol isolated from brown algae Ecklonia cava has been reported to possess inhibitory
activity against 3CLpro or Mpro of SARS-CoV [… (Dieckol) as the most promising inhibitor of the …

… from Ecklonia cava, an edible marine algae, as inhibitors of … dieckol (DEK) as the most potent
SARS-CoV Mpro inhibitory. … species ie Ecklonia cava (commonly known as brown algae) …

… E (isolated from Angelica keiskei), dieckol 1 (isolated from … that inhibit SARS-CoV 3CL
pro activity, including Angelica keiskei (Miq.) Koidz., Salvia miltiorrhiza Bunge, Ecklonia cava …

… ) extracted from Ecklonia cava (edible brown algae) that showed potent inhibitory activity
against SARS-CoV-1 3CLpro … the inhibitory effect of dieckol against SARS-CoV 3CLpro with a …

… from the brown alga Ecklonia cava against the PEDL. The … phlorofucofuroeckol and
dieckol from the brown seaweed E. … cava as an inhibitor of PLpro of the SARS-CoV virus. The …

… , dieckol had a competitive inhibitory effect on the SARS-CoV … -bieckol and dieckol produced
from the marine brown alga E. … After infection, SARS-CoV 3CLpro substantially enhances …

… were isolated in the brown algae Ecklonia cava in wild … Dieckol is a phlorotannin compound
extracted from Ecklonia … their competitive inhibition characteristics to the SARS-CoV 3CLpro, …

… SARSCoV- inhibitors. The phlorotannins 6,6-bieckol, 8,8-bieckol and dieckol produced from
the marine brown alga E. … by phlorotannins from the brown alga Ecklonia cava. Biol. Pharm. …