Diffusion-weighted magnetic resonance imaging of ovarian tumors: differentiation of benign and malignant solid components of ovarian masses

M Takeuchi, K Matsuzaki… - Journal of computer …, 2010 - journals.lww.com
M Takeuchi, K Matsuzaki, H Nishitani
Journal of computer assisted tomography, 2010•journals.lww.com
Objective: We evaluated the feasibility of diffusion-weighted imaging (DWI) with apparent
diffusion coefficient (ADC) measurement in differentiating benign and malignant ovarian
tumors. Methods: Surgically proven 49 ovarian tumors (39 malignant/borderline malignant
and 10 benign) were examined. Results: The solid portion of all 39 malignant tumors
showed homogeneous or heterogeneous high intensity on DWI, whereas only 3 of the 10
benign tumors (3 thecomas) showed high intensity. The mean (SD) ADC value in the 39 …
Abstract
Objective:
We evaluated the feasibility of diffusion-weighted imaging (DWI) with apparent diffusion coefficient (ADC) measurement in differentiating benign and malignant ovarian tumors.
Methods:
Surgically proven 49 ovarian tumors (39 malignant/borderline malignant and 10 benign) were examined.
Results:
The solid portion of all 39 malignant tumors showed homogeneous or heterogeneous high intensity on DWI, whereas only 3 of the 10 benign tumors (3 thecomas) showed high intensity. The mean (SD) ADC value in the 39 malignant tumors (1.03 [0.19]) was significantly lower than that in 10 benign tumors (1.38 [0.30]). A relatively low ADC (1.08-1.20) in the 3 thecomas may reflect their abundant cellular nature, and the presence of low intensity on T2-weighted images was suggestive for benign fibrous tumor.
Conclusions:
Low intensity on DWI with high ADC may suggest benign lesions; however, it may be occasionally difficult to differentiate benign and malignant lesions only on the basis of DWI.
Lippincott Williams & Wilkins
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