… and apoptosis through the JNK/p38 pathway. In vivo, dioscin significantly inhibited OS …
Taken together, our results demonstrate that dioscin can induce apoptosis through the JNK/p38 …

… dioscin inhibits the growth of human osteosarcoma by inducing G2/M phase arrest, apoptosis,
… ‐dependent cell death, and also inhibits stem cell‐like characteristics and tumor growth of …

… ten human osteosarcoma cell lines were sensitive to dioscin … e Dioscin induces a G2/M phase
arrest in osteosarcoma … further found that dioscin efficiently induced apoptosis in OS cells. …

… Dioscin can induce G2/M phase arrest and apoptosis in SGC-7901 cells by inhibiting CDK-…
Liu, WH et al., have adopted in vitro and in vivo models, and dioscin inhibits osteosarcoma …

… that DS suppresses the growth of OS cells by inducing G2/M‐phase arrest, apoptosis, and
… demonstrated that DS inhibited viability and metastasis, while induced apoptosis in OS cells, …

… Dioscin-enhanced ERβ levels to induce cell apoptosis … osteosarcoma cells via caspase-3-dependent
cleavage of gasdermin E, inhibiting tumor cell growth through G2/M cell cycle arrest…

… of G2/M phase cells increased with concentration of diosgenin. … in osteosarcoma cells and
C3A hepatoma cells (14,15), … that diosgenin inhibited HCC cell proliferation by inducing G2/M …

… found diosgenin inhibited cell growth and induced apoptosis. … Moreover, diosgenin
exposure led to G2/M cell cycle arrest … Human osteosarcoma cell lines U2OS and MG63 were …

… S and G2/M cells, suggesting the induction of cell cycle arrest by AMP at the G0/G1 phase. …
QY (2005) Diosgenin induces cell cycle arrest and apoptosis in human leukemia K562 cells …

… this inhibition involved arresting the cell cycle at the G2/M phase by … diosgenin induces a
significant cell cycle arrest at the G2/M phase, leading to p53-independent apoptosis of human …