Direct drug susceptibility testing of Mycobacterium tuberculosis against primary anti-TB drugs in northern India

A Gupta, S Anupurba - The Journal of Infection in Developing Countries, 2010 - jidc.org
Introduction: The present study aimed to evaluate a rapid and inexpensive colorimetric
nitrate reductase assay (NRA) performed directly on sputum specimens for detection of drug
resistance in Mycobacterium tuberculosis (MTB). Methodology: A total of 55 sputum samples
were decontaminated and processed by modified Petroff's method. A part of the resulting
suspension was used to perform direct NRA (DNRA) and direct proportion method (DPM)
analysis. Of the 55 samples, 45 could be used to compare the two methods. Indirect drug …

Direct drug susceptibility testing of Mycobacterium tuberculosis against primary anti-TB drugs in northern India.

AG Anamika Gupta, SA Shampa Anupurba - 2010 - cabidigitallibrary.org
Introduction: The present study aimed to evaluate a rapid and inexpensive colorimetric
nitrate reductase assay (NRA) performed directly on sputum specimens for detection of drug
resistance in Mycobacterium tuberculosis (MTB). Methodology: A total of 55 sputum samples
were decontaminated and processed by modified Petroff's method. A part of the resulting
suspension was used to perform direct NRA (DNRA) and direct proportion method (DPM)
analysis. Of the 55 samples, 45 could be used to compare the two methods. Indirect drug …
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