Dissociated expression of Bcl-2 and Ki-67 in endometrial lesions: diagnostic and histogenetic implications

B Risberg, K Karlsson, V Abeler… - International journal …, 2002 - journals.lww.com
The objective of the present study was to analyze the expression of the proliferation marker,
Ki-67, and the anti-apoptotic protein, bcl-2, in various endometrial lesions. Ki-67 and bcl-2
expressions were studied in 194 specimens of endometrial hyperplasia, polyps, carcinomas,
and cyclic endometrium from a defined geographic area. Results were statistically analyzed
with respect to marker expression, localization to the stromal or glandular component, and
intraglandular topography. The lowest glandular Ki-67 expression was seen in secretory …
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