Drug screening of food and drug administration-approved compounds against Babesia bovis in vitro

Y Li, M Liu, MA Rizk, PFA Moumouni, SH Lee… - Experimental …, 2020 - Elsevier
Babesia (B.) bovis is one of the main etiological agents of bovine babesiosis, causes serious
economic losses to the cattle industry. Control of bovine babesiosis has been hindered by
the limited treatment selection for B. bovis, thus, new options are urgently needed. We
explored the drug library and unbiasedly screened 640 food and drug administration (FDA)
approved drug compounds for their inhibitory activities against B. bovis in vitro. The initial
screening identified 13 potentially effective compounds. Four potent compounds, namely …
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