Dynamic changes in microvascular flow conductivity and perfusion after myocardial infarction shown by image‐based modeling
Background Microcirculation is a decisive factor in tissue reperfusion inadequacy following
myocardial infarction (MI). Nonetheless, experimental assessment of blood flow in
microcirculation remains a bottleneck. We sought to model blood flow properties in coronary
microcirculation at different time points after MI and to compare them with healthy conditions
to obtain insights into alterations in cardiac tissue perfusion. Methods and Results We
developed an image‐based modeling framework that permitted feeding a continuum flow …
myocardial infarction (MI). Nonetheless, experimental assessment of blood flow in
microcirculation remains a bottleneck. We sought to model blood flow properties in coronary
microcirculation at different time points after MI and to compare them with healthy conditions
to obtain insights into alterations in cardiac tissue perfusion. Methods and Results We
developed an image‐based modeling framework that permitted feeding a continuum flow …
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