Dynamics of the IL-33/ST2 network in the progression of human colorectal adenoma to sporadic colorectal cancer

G Cui, H Qi, MD Gundersen, H Yang… - Cancer Immunology …, 2015 - Springer
Most sporadic colorectal cancers (CRCs) develop from preformed adenomas. Cytokines are
involved in the transition from adenoma to CRC. Interleukin-33 (IL-33) is a newly discovered
proinflammatory cytokine belonging to the IL-1 cytokine family and involved in the
development of chronic inflammation and cancer. The aim of this study was to evaluate the
dynamics of the IL-33/ST2 axis during the sequence of progression from normal colorectum
to adenoma to carcinoma and to investigate the association of IL-33 and ST2 expression …

Dynamics of the IL-33/ST2 network in the progression of human colorectal adenoma to sporadic colorectal cancer

C Guanglin, H Qi, MD Gundersen, H Yang… - 2014 - munin.uit.no
Most sporadic colorectal cancers (CRCs) develop from preformed adenomas. Cytokines are
involved in the transition from adenoma to CRC. Interleukin-33 (IL-33) is a newly discovered
proinflammatory cytokine belonging to the IL-1 cytokine family and involved in the
development of chronic inflammation and cancer. The aim of this study was to evaluate the
dynamics of the IL-33/ST2 axis during the sequence of progression from normal colorectum
to adenoma to carcinoma and to investigate the association of IL-33 and ST2 expression …
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