… Blocking TGF-β up-regulates E-cadherin and reduces migration and invasion of hepatocellular
carcinoma cells[10]. Furthermore, liver tumors expressing late TGF-β-responsive genes (…

… of apoptosis regulation in hepatocellular carcinomas. Due to … number of excellent reviews
on apoptosis, both general as well … apoptosis in the liver and its dysregulation in hepatocellular …

… The histone deacetylase inhibitor suberoylanilide hydroxamic acid sensitises human
hepatocellular carcinoma cells to TRAIL-induced apoptosis by TRAIL-DISC activation. Eur. J…

… apoptosis is regulated and whether or not its dysregulation might … towards a hepatocellular
carcinoma (HCC) process. … inactivated in HCC, such as Fas, p53, Bax or Bid, dysregulation of …

… for inducing apoptosis in hepatocellular carcinoma cells, however, … apoptosis may be useful
in preventing tumor spread and colonization within the liver. Hepatocellular carcinoma cells …

… Dysregulation of pleiotropic growth factors, … of tumor cells. This review focuses on the relevant
alterations in these pathways identified in human human hepatocellular carcinomas (HCCs…

… cancer cell migration and invasion in HCC.48, 49 In addition, miR-21 could be a predictor of
the clinical course in patients with HCC.50, 51 The key miRNA-21 targets tumor … cell death-4 …

… and patients with hepatocellular carcinoma using a … in hepatocellular carcinoma, we
performed the IL-32 siRNA experiments. We examined cell survival/growth, cell cycle and apoptosis …

… Metabolic dysregulation is emphasized in the pathogenesis of hepatocellular carcinoma (HCC),
thus agents or chemicals are developed as potentials to treat HCC by targeting …

… of its effects on tumor cells and the stroma. We also seek to evaluate the dysregulation
mechanisms that mediate the functional switch of TGF-β from a tumor suppressor to a pro-…