EGFR, ERBB2, and KRAS mutations in Korean non-small cell lung cancer patients
NC Bae, MH Chae, MH Lee, KM Kim, EB Lee… - Cancer genetics and …, 2007 - Elsevier
The epidermal growth factor receptor (EGFR), and its family members play an important role
in the development and progression of lung cancers. It has been reported that somatic
mutations in the tyrosine kinase domain of the EGFR or ERBB2 genes occur in a subset of
patients with lung cancer. We searched for mutations of the EGFR, ERBB2, and KRAS
genes in surgically resected non-small cell lung cancers (NSCLCs) to determine the
prevalence of these mutations in Korean lung cancer patients. In addition, we examined the …
in the development and progression of lung cancers. It has been reported that somatic
mutations in the tyrosine kinase domain of the EGFR or ERBB2 genes occur in a subset of
patients with lung cancer. We searched for mutations of the EGFR, ERBB2, and KRAS
genes in surgically resected non-small cell lung cancers (NSCLCs) to determine the
prevalence of these mutations in Korean lung cancer patients. In addition, we examined the …
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