Early blastocyst expansion in euploid and aneuploid human embryos: evidence for a non-invasive and quantitative marker for embryo selection
TTF Huang, DH Huang, HJ Ahn, C Arnett… - Reproductive …, 2019 - Elsevier
Research question How can the kinetics of human blastocyst expansion be used to evaluate
an embryo's ploidy identified using preimplantation genetic testing for aneuploidy (PGT-A)?
Design This was a retrospective observational study of 188 autologous blastocysts from 34
sequential treatment cycles using PGT-A and blastocyst biopsy. Using time-lapse imaging,
blastocyst expansion was evaluated using a quantitative standardized expansion assay
(qSEA). Trophectoderm cell division was examined in selected, unbiopsied embryos (n= 7) …
an embryo's ploidy identified using preimplantation genetic testing for aneuploidy (PGT-A)?
Design This was a retrospective observational study of 188 autologous blastocysts from 34
sequential treatment cycles using PGT-A and blastocyst biopsy. Using time-lapse imaging,
blastocyst expansion was evaluated using a quantitative standardized expansion assay
(qSEA). Trophectoderm cell division was examined in selected, unbiopsied embryos (n= 7) …
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