Fishing, hunting, and wildlife-associated recreation expenditures have played an important role in the US economy. The 2006 US Fish and Wildlife Service survey reported 87.5 million people participated in wildlife-associated recreation activities, spending $122.4 billion on trips and equipment in US Periodic assessment of economic impact of wildlife associated recreation provides a consistent perspective for forest and wildlife resource management. This research used input-output analysis to evaluate the economic impacts of wildlife associated recreation expenditures in the US South. IMPLAN models were developed for each state to determine the direct, indirect and induced effects of these expenditures. The comparison revealed the differences in the individual states' economies and levels of expenditures and illustrated the importance of understanding intra-regional variations in establishing wildlife programs and policies. Overall, this study shows that wildlife associated recreation expenditures had larger economic multiplier than of the other forest based industries in the US South.