Background Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease in
the United States; 85%–95% of the morbidly obese population have NAFLD and 33% have
nonalcoholic steatohepatitis. There is a lack of comparative data assessing various bariatric
procedures and their effect on NAFLD. Objectives To assess and compare the effects of
Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG) on NAFLD. Setting
Academic Center, United States Methods All bariatric cases performed at the authors' …

Roux-en-Y gastric bypass (RYGB) improves, and can sometimes resolve, non-alcoholic fatty
liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) but data based on
histological assessment for the efficacy of sleeve gastrectomy (SG) in resolving NAFLD are
sparse. Consequently, we aimed to compare the efficacy of RYGB vs. SG on NAFLD 12
months after surgery. In a prospective cohort study, 40 patients with obesity underwent
bariatric surgery (16 RYGB and 24 SG). During surgery, a liver biopsy was taken and …