Effect of citral, eugenol, nerolidol and α-terpineol on the ultrastructural changes of Trichophyton mentagrophytes

MJ Park, KS Gwak, I Yang, KW Kim, EB Jeung… - Fitoterapia, 2009 - Elsevier
The antifungal effects of citral, eugenol, nerolidol and α-terpineol on Trichophyton
mentagrophytes were investigated. Citral over 0.1 mg/ml strongly inhibited the hyphal
growth of T. mentagrophytes, and the antifungal activity of α-terpineol was less effective. The
morphological changes of the fungus exposed to the terpenes were observed by electron
microscopy. The hyphae were distorted and collapsed at 0.2, 0.4 and 1 mg/ml of eugenol,
nerolidol and α-terpineol respectively, and cell membrane and organelles were irreversibly …
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