Effect of combined exercise training on serum brain-derived neurotrophic factor, suppressors of cytokine signaling 1 and 3 in patients with multiple sclerosis

C Ozkul, A Guclu-Gunduz, C Irkec, I Fidan… - Journal of …, 2018 - Elsevier
Background Suppressors of cytokine signaling (SOCS) and brain-derived neurotrophic
factor (BDNF) are important immunologic, and neurotrophic factors for MS pathogenesis.
The impact of exercise on these factors is yet to be fully elucidated in patients with MS.
Objective The primary aim of this study is to investigate the effect of 8-week combined
exercise training on serum concentrations of SOCS1, SOCS3, and BDNF. The secondary
aim is to determine the effects of combined exercise training on balance, functional exercise …
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