COVID-19 is inconclusive. Objective To determine whether convalescent plasma would
improve outcomes for critically ill adults with COVID-19. Design, Setting, and Participants
The ongoing Randomized, Embedded, Multifactorial, Adaptive Platform Trial for Community-
Acquired Pneumonia (REMAP-CAP) enrolled and randomized 4763 adults with suspected
or confirmed COVID-19 between March 9, 2020, and January 18, 2021, within at least 1 …