respiratory failure and is widely applied in patients with COVID-19. Objective To assess
whether helmet noninvasive ventilation can increase the days free of respiratory support in
patients with COVID-19 compared with high-flow nasal oxygen alone. Design, Setting, and
Participants Multicenter randomized clinical trial in 4 intensive care units (ICUs) in Italy
between October and December 2020, end of follow-up February 11, 2021, including 109 …