Effect of increasing doses of aspirin on platelet function as measured by PFA-100 in patients with diabetes
INTRODUCTION: Platelets of diabetic patients have been reported to be less sensitive to
aspirin. The aim of this study is to compare a medium (300 mg) and low (100 mg) dose of
aspirin on platelet function in diabetic patients. METHODS: We have included one hundred
and two patients with type 2 diabetes mellitus. Platelet function was measured as closure
time (CT) with the Platelet Function Analyzer (PFA)-100™ before the administration of
aspirin. Initially the patients were given 100 mg aspirin once daily for seven days, and then …
aspirin. The aim of this study is to compare a medium (300 mg) and low (100 mg) dose of
aspirin on platelet function in diabetic patients. METHODS: We have included one hundred
and two patients with type 2 diabetes mellitus. Platelet function was measured as closure
time (CT) with the Platelet Function Analyzer (PFA)-100™ before the administration of
aspirin. Initially the patients were given 100 mg aspirin once daily for seven days, and then …
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