Effect of preradiation dental intervention on incidence of osteoradionecrosis in patients with head and neck cancer: A systematic review and meta-analysis

O Urquhart, HR DeLong, KM Ziegler, L Pilcher… - The Journal of the …, 2022 - Elsevier
Background The purpose of this systematic review was to examine whether dental
intervention involving bone or soft-tissue manipulation preradiotherapy (pre-RT) is
associated with lower rates of osteoradionecrosis of the jaw (ORNJ) in patients with head
and neck cancer (HNC). Types of Studies Reviewed The authors included relevant studies
from MEDLINE, Embase, and Cochrane Library, including observational studies published
from 2007 through 2021 and involving adults who underwent dental intervention pre-RT for …
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