Recurrent head and neck malignancies (HNM) are often radio-/chemo-resistant and show
extensive growth, necessitating a wide resection including surrounding tissues. To avoid
severe impairment of oro-facial structures and functions, it is necessary to explore new
treatments for HNM. Boron neutron capture therapy (BNCT) is tumor-cell targeted
radiotherapy that has significant superiority over conventional radiotherapies in principle.
We report here, first in the world, six patients with a recurrent HNM who have been treated …