[HTML][HTML] Effects of YC-1 on learning and memory functions of aged rats
Medical science monitor basic research, 2014•ncbi.nlm.nih.gov
… With this background, we aimed to investigate the role of long-term YC-1 treatment on
acquisition and retention of memory in aged rats using 4 month-old and 24-month-old rats
in the Morris water maze and passive avoidance tests. … Our results suggest that
improvement of age-related learning and memory deficits via chronic YC-1 treatment may
result from the direct effects of YC-1 on sGC. In the present study, YC-1 was used as a tool
for investigating sGC and cGMP-mediated pathways on aging. It is well known that the …
acquisition and retention of memory in aged rats using 4 month-old and 24-month-old rats
in the Morris water maze and passive avoidance tests. … Our results suggest that
improvement of age-related learning and memory deficits via chronic YC-1 treatment may
result from the direct effects of YC-1 on sGC. In the present study, YC-1 was used as a tool
for investigating sGC and cGMP-mediated pathways on aging. It is well known that the …
Abstract
Background
The aim of this study was to investigate the effects of a potent nitric oxide-guanylate cyclase activator, 3-(5′-hydroxymethyl-2′-furyl)-1-benzylindazole (YC-1), on learning and memory functions in aged rats.
ncbi.nlm.nih.gov
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