Effects of a home‐based exercise program on anxiety and mood disturbances in older adults with cancer receiving chemotherapy
KP Loh, IR Kleckner, PJ Lin, SG Mohile… - Journal of the …, 2019 - Wiley Online Library
Journal of the American Geriatrics Society, 2019•Wiley Online Library
BACKGROUND/OBJECTIVE Exercise interventions improve anxiety and mood disturbances
in patients with cancer. However, studies are limited in older adults with cancer. We
assessed the effects of exercise on anxiety, mood, and social and emotional well‐being in
older patients with cancer during their first 6 weeks of chemotherapy. DESIGN Exploratory
secondary analysis of a randomized controlled trial (RCT). SETTING Community oncology
practices. PARTICIPANTS Older patients (aged 60 years or older) undergoing …
in patients with cancer. However, studies are limited in older adults with cancer. We
assessed the effects of exercise on anxiety, mood, and social and emotional well‐being in
older patients with cancer during their first 6 weeks of chemotherapy. DESIGN Exploratory
secondary analysis of a randomized controlled trial (RCT). SETTING Community oncology
practices. PARTICIPANTS Older patients (aged 60 years or older) undergoing …
BACKGROUND/OBJECTIVE
Exercise interventions improve anxiety and mood disturbances in patients with cancer. However, studies are limited in older adults with cancer. We assessed the effects of exercise on anxiety, mood, and social and emotional well‐being in older patients with cancer during their first 6 weeks of chemotherapy.
DESIGN
Exploratory secondary analysis of a randomized controlled trial (RCT).
SETTING
Community oncology practices.
PARTICIPANTS
Older patients (aged 60 years or older) undergoing chemotherapy (N = 252).
INTERVENTION
Patients were randomized to Exercise for Cancer Patients (EXCAP) or usual care (control) for the first 6 weeks of chemotherapy. EXCAP is a home‐based, low‐ to moderate‐intensity progressive walking and resistance training program.
MEASUREMENTS
Analysis of covariance, with study arm as the factor, baseline value as the covariate, and study arm × baseline interaction, was used to evaluate arm effects on postintervention anxiety (State Trait Anxiety Inventory [STAI]), mood (Profile of Mood States [POMS]), and social and emotional well‐being (Functional Assessment of Cancer Therapy–General subscales) after 6 weeks.
RESULTS
Median age was 67 years; 77% had breast cancer. Statistically significant group differences were observed in the STAI score (P = .001), POMS score (P = .022), social well‐being (P = .002), and emotional well‐being (P = .048). For each outcome, EXCAP patients with worse baseline scores had larger improvements at 6 weeks; these improvements were clinically significant for STAI score and social well‐being.
CONCLUSIONS
Among older cancer patients receiving chemotherapy, a 6‐week structured exercise program improved anxiety and mood, especially among those participants with worse baseline symptoms. Additional RCTs are needed to confirm these findings and evaluate the appropriate exercise prescription for managing anxiety, mood, and well‐being in this patient population. J Am Geriatr Soc 67:1005–1011, 2019.
Wiley Online Library以上显示的是最相近的搜索结果。 查看全部搜索结果