The RFamide peptide family comprises a number of biologically active peptides sharing RF
motif at their C-terminal end. These peptides are involved in the control of multiple
physiological functions including regulation of metabolism and feeding behavior. QRFP-43
as well as its 26-aminoacid residue QRFP-26 are able to cause orexigenic effect when
administered to the rodents' cerebral ventricles. QRFPs have been suggested as the
endogenous ligands of the previously orphan GPR103 receptors. GPR103 receptors share …