Effects of serial macrocyclic-based contrast materials gadoterate meglumine and gadobutrol administrations on gadolinium-related dentate nuclei signal increases in …
A Splendiani, M Perri, C Marsecano, V Vellucci… - La radiologia …, 2018 - Springer
Purpose To perform T1 signal intensity (SI) measurements in the dentate nuclei of adult
patients with confirmed multiple sclerosis (MS) after serial administrations of the macrocyclic
gadolinium-based contrast agents (GBCAs), gadoterate meglumine and gadobutrol.
Materials and methods This retrospective study was approved by the institutional review
board and informed consent was waived. A review of our PACS database for the period from
March 1, 2007 to July 31, 2016 revealed 158 confirmed MS patients who received …
patients with confirmed multiple sclerosis (MS) after serial administrations of the macrocyclic
gadolinium-based contrast agents (GBCAs), gadoterate meglumine and gadobutrol.
Materials and methods This retrospective study was approved by the institutional review
board and informed consent was waived. A review of our PACS database for the period from
March 1, 2007 to July 31, 2016 revealed 158 confirmed MS patients who received …
Re: effects of serial macrocyclic-based contrast materials gadoterate meglumine and gadobutrol administrations on gadolinium-related dentate nuclei signal increases …
JS Raynaud, E Darmon-Kern, E Lancelot… - La radiologia …, 2018 - Springer
In the September 2017 on‐line issue of La Radiologia Medica, Splendiani et al. published a
clinical study on the effects of multiple injections of the macrocyclic GBCAs gadoterate
meglumine and gadobutrol on dentate nuclei T1-weighted signal intensities (SI) in patients
with multiple sclerosis [1]. In the abstract, the authors concluded:“SI increases on
unenhanced T1-weighted images possibly indicative of gadolinium retention occur after
serial administrations of the macrocyclic GBCAs, gadoterate meglumine and gadobutrol” …
clinical study on the effects of multiple injections of the macrocyclic GBCAs gadoterate
meglumine and gadobutrol on dentate nuclei T1-weighted signal intensities (SI) in patients
with multiple sclerosis [1]. In the abstract, the authors concluded:“SI increases on
unenhanced T1-weighted images possibly indicative of gadolinium retention occur after
serial administrations of the macrocyclic GBCAs, gadoterate meglumine and gadobutrol” …
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