[HTML][HTML] Effects of vitamin D and calcium supplementation on pancreatic β cell function, insulin sensitivity, and glycemia in adults at high risk of diabetes: the Calcium …

J Mitri, B Dawson-Hughes, FB Hu, AG Pittas - The American journal of …, 2011 - Elsevier
Background: A suboptimal vitamin D and calcium status has been associated with higher
risk of type 2 diabetes in observational studies, but evidence from trials is lacking. Objective:
We determined whether vitamin D supplementation, with or without calcium, improved
glucose homeostasis in adults at high risk of diabetes. Design: Ninety-two adults were
randomly assigned in a 2-by-2 factorial-design, double-masked, placebo-controlled trial to
receive either cholecalciferol (2000 IU once daily) or calcium carbonate (400 mg twice daily) …
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