Emergence of host-adapted Salmonella Enteritidis through rapid evolution in an immunocompromised host
EJ Klemm, E Gkrania-Klotsas, J Hadfield… - Nature …, 2016 - nature.com
Host adaptation is a key factor contributing to the emergence of new bacterial, viral and
parasitic pathogens. Many pathogens are considered promiscuous because they cause
disease across a range of host species, while others are host-adapted, infecting particular
hosts 1. Host adaptation can potentially progress to host restriction, where the pathogen is
strictly limited to a single host species and is frequently associated with more severe
symptoms. Host-adapted and host-restricted bacterial clades evolve from within a broader …
parasitic pathogens. Many pathogens are considered promiscuous because they cause
disease across a range of host species, while others are host-adapted, infecting particular
hosts 1. Host adaptation can potentially progress to host restriction, where the pathogen is
strictly limited to a single host species and is frequently associated with more severe
symptoms. Host-adapted and host-restricted bacterial clades evolve from within a broader …
[引用][C] Emergence of hostadapted Salmonella Enteritidis through rapid evolution in an immunocompromised host. Nat Microbiol 1: 15023
EJ Klemm, E Gkrania-Klotsas, J Hadfield, JL Forbester… - 2015
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