[PDF][PDF] Endometriosis: A brief review of Pharmacological and Non-Pharmacological Treatment

SA Ali, S Ali, S Rastogi, J Prasad, P Kondrapu… - vol - researchgate.net
SA Ali, S Ali, S Rastogi, J Prasad, P Kondrapu, B Kumar, A Sharma, K Pandey…
volresearchgate.net
Endometriosis is regarded as a spectrum disease with a wide range of subtypes and clinical
manifestations. Endometriosis must be found to be present outside of (ectopic) the uterus in
order to be defined histologically. These ectopic lesions are frequently found on the
peritoneum and pelvic organs. They may occasionally exist in the bladder, kidneys, lungs,
and even the brain, among other body organs. Regarding behavioral characteristics,
research has been done on the connection between dietary preferences, alcohol and …
Abstract
Endometriosis is regarded as a spectrum disease with a wide range of subtypes and clinical manifestations. Endometriosis must be found to be present outside of (ectopic) the uterus in order to be defined histologically. These ectopic lesions are frequently found on the peritoneum and pelvic organs. They may occasionally exist in the bladder, kidneys, lungs, and even the brain, among other body organs. Regarding behavioral characteristics, research has been done on the connection between dietary preferences, alcohol and caffeine consumption, smoking, and physical activity in relation to involvement in developing endometriosis. Normal responses to progesterone in the uterine endometrium include suppression of estrogen-dependent epithelial cell proliferation, maturation of the glands' secretory systems, and differentiation of stromal cells into specialized decidual cells. Additionally, progesterone briefly produces the receptive phenotype necessary for embryo implantation in endometrial epithelial cells. Pain is one of its predominant clinical features. Women with endometriosis experience a variety of pain symptoms, most commonly dysmenorrhea, noncyclical pelvic pain, dyspareunia, and dyschezia. The experience of pain, no matter what the underlying disease, involves several different mechanisms and interactions between the periphery and the central nervous system (CNS).
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