… HIF-2α regulates EC function and tissue perfusion under physiological and pathological …
demonstrate here that HIF-2α expression is required for angiogenic responses during hindlimb …

… Since endothelial HIF-2 regulated IRI-associated … Taken together, our studies identified
endothelial HIF-2α as a … in the regulation of tumor angiogenesis and wound healing (20, 26…

The authors recently became aware that the image presented in Figure 4A for the 21% O2 KO
H2. 1 sample was a different crop as the image presented in Figure 4A for the 21% O2 Ctrl …

… Because HIF-2α is a key transcription factor that regulates various angiogenesis-related genes,
4 we … Although we establish that the loss of endothelial HIF-2α in mice is associated with …

… HIF-2α is also regulated by a similar mechanism. Hypoxia … a processes called diapesis,
squeezing between endothelial cells … The ability of VEGF to regulate pathologic angiogenesis in …

… list of angiogenic processes regulated by them truly make … tumors in mice with
endothelial-specific Hif-2α deletion are … of therapeutic angiogenesis and revascularization after …

… Dll4 and Dll4/Ang2 are sufficient to reverse endothelial HIF-2α deletion phenotypes in a
hindlimb ischemia model. Blood flow, foot movement score and necrosis were assessed for Ctrl …

… endothelial growth factor (VEGF) was a direct target of HIF-2α and that HIF-1α and HIF-2α
regulated … angiogenesis and revascularization processes. J Clin Invest 122, 1427–1443, doi: …

… Immunohistochemistry methods were described in detail … Another report suggested that
endothelial HIF-2α regulates … whether therapeutic angiogenesis was induced by specific HIF-2α …

… However, besides the initiation of the angiogenesis process … of HIF-2α in the regulation of
angiogenesis in mouse lungs. … neovascularization in several pathological conditions, such as …