Endovascular thrombectomy for large ischemic stroke across ischemic injury and penumbra profiles

A Sarraj, AE Hassan, MG Abraham, S Ortega-Gutierrez… - JAMA, 2024 - jamanetwork.com
Importance Whether endovascular thrombectomy (EVT) efficacy for patients with acute
ischemic stroke and large cores varies depending on the extent of ischemic injury is
uncertain. Objective To describe the relationship between imaging estimates of irreversibly
injured brain (core) and at-risk regions (mismatch) and clinical outcomes and EVT treatment
effect. Design, Setting, and Participants An exploratory analysis of the SELECT2 trial, which
randomized 352 adults (18-85 years) with acute ischemic stroke due to occlusion of the …
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