Endovascular treatment for Small Core and Anterior circulation Proximal occlusion with Emphasis on minimizing CT to recanalization times (ESCAPE) trial …
ESCAPE is a prospective, multicenter, randomized clinical trial that will enroll subjects with
the following main inclusion criteria: less than 12 h from symptom onset, age> 18, baseline
NIHSS> 5, ASPECTS score of> 5 and CTA evidence of carotid T/L or M1 segment MCA
occlusion, and at least moderate collaterals by CTA. The trial will determine if endovascular
treatment will result in higher rates of favorable outcome compared with standard medical
therapy alone. Patient populations that are eligible include those receiving IV tPA, tPA …
the following main inclusion criteria: less than 12 h from symptom onset, age> 18, baseline
NIHSS> 5, ASPECTS score of> 5 and CTA evidence of carotid T/L or M1 segment MCA
occlusion, and at least moderate collaterals by CTA. The trial will determine if endovascular
treatment will result in higher rates of favorable outcome compared with standard medical
therapy alone. Patient populations that are eligible include those receiving IV tPA, tPA …
Endovascular treatment for small core and anterior circulation proximal occlusion with emphasis on minimizing CT to recanalization times (ESCAPE)
MD Hill - International Stroke Conference, 2015 - stroke.or.kr
_~ إقضيهٌماW= There is no convincing, randomized trial evidence that modern endovascular
therapy is better than routine care, including routine intravenous thrombolysis, for acute
ischemic stroke. There is nevertheless, strong evidence that endovascular therapy can result
in faster, more complete recanalization (high recanalization rates of about 80%) and that this
should result in better stroke outcomes. Patients with a small core of infarct but a significant
clinical deficit do benefit from reperfusion even at late time windows. lؤـةإٍفَةW The ESCAPE …
therapy is better than routine care, including routine intravenous thrombolysis, for acute
ischemic stroke. There is nevertheless, strong evidence that endovascular therapy can result
in faster, more complete recanalization (high recanalization rates of about 80%) and that this
should result in better stroke outcomes. Patients with a small core of infarct but a significant
clinical deficit do benefit from reperfusion even at late time windows. lؤـةإٍفَةW The ESCAPE …