Engineering tolerance and accumulation of lead and cadmium in transgenic plants

WY Song, E Ju Sohn, E Martinoia, Y Jik Lee… - Nature …, 2003 - nature.com
We have studied the utility of the yeast protein YCF1, which detoxifies cadmium by
transporting it into vacuoles, for the remediation of lead and cadmium contamination. We
found that the yeast YCF1-deletion mutant DTY167 was hypersensitive to Pb (ii) as
compared with wild-type yeast. DTY167 cells overexpressing YCF1 were more resistant to
Pb (ii) and Cd (ii) than were wild-type cells, and accumulated more lead and cadmium.
Analysis of transgenic Arabidopsis thaliana plants overexpressing YCF1 showed that YCF1 …

Engineering tolerance and accumulation of lead and cadmium in transgenic plants.

SWY Song WonYong, SEJ Sohn EunJu, E Martinoia… - 2003 - cabidigitallibrary.org
We have studied the utility of the yeast protein YCF1, which detoxifies cadmium by
transporting it into vacuoles, for the remediation of lead and cadmium contamination. We
found that the yeast YCF1-deletion mutant DTY167 was hypersensitive to Pb (II) compared
with wild-type yeast. DTY167 cells overexpressing YCF1 were more resistant to Pb (II) and
Cd (II) than were wild-type cells, and accumulated more lead and cadmium. Analysis of
transgenic Arabidopsis thaliana plants overexpressing YCF1 showed that YCF1 is …
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