transporting it into vacuoles, for the remediation of lead and cadmium contamination. We
found that the yeast YCF1-deletion mutant DTY167 was hypersensitive to Pb (ii) as
compared with wild-type yeast. DTY167 cells overexpressing YCF1 were more resistant to
Pb (ii) and Cd (ii) than were wild-type cells, and accumulated more lead and cadmium.
Analysis of transgenic Arabidopsis thaliana plants overexpressing YCF1 showed that YCF1 …