Enhanced in vivo function of bioartificial lungs in rats
JJ Song, SS Kim, Z Liu, JC Madsen… - The Annals of thoracic …, 2011 - Elsevier
BACKGROUND: More than 11 million Americans live with chronic lung disease; in search
for an alternative to donor organs, we attempted to regenerate lungs based on perfusion
decellularized lung scaffolds that can be transplanted similar to a donor organ. METHODS:
Cadaveric rat lungs were decellularized by detergent perfusion. Resulting scaffolds were
mounted in bioreactors and seeded with endothelial and fetal lung cells. Biomimetic organ
culture was maintained for 7 days. Resulting bioartificial left lungs were transplanted in …
for an alternative to donor organs, we attempted to regenerate lungs based on perfusion
decellularized lung scaffolds that can be transplanted similar to a donor organ. METHODS:
Cadaveric rat lungs were decellularized by detergent perfusion. Resulting scaffolds were
mounted in bioreactors and seeded with endothelial and fetal lung cells. Biomimetic organ
culture was maintained for 7 days. Resulting bioartificial left lungs were transplanted in …
[引用][C] Enhanced In Vivo Function of Bioartificial Lungs in Rats DISCUSSION
TK Waddell, D Van Raemdonck - Annals of Thoracic …, 2011 - lirias.q.icts.kuleuven.be
Enhanced In Vivo Function of Bioartificial Lungs in Rats DISCUSSION … Enhanced In Vivo
Function of Bioartificial Lungs in Rats DISCUSSION …
Function of Bioartificial Lungs in Rats DISCUSSION …
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