This study attempts to design data security and privacy of healthcare centers mainly found in Addis Ababa city including both public and private health centers. Most of the Ethiopian healthcare centers are keeping their confidential records in a manual way. Records of patients, healthcare centers and other communication letters that are shared with other centers need privacy and security. However, nowadays there is no clear framework used to share health information among healthcare centers, which the current study targeted to deal with. The current study has been conducted based on the design science research process. Problems were identified using surveys conducted by distributing questionnaires to the health institutions. The collected data were analyzed and interpreted to define the problem and motivate the need to design a framework. This stage leads the researcher to define the system requirement and design the system framework. The prototype is implemented using the JAVA programming language. The prototype is needed to be integrated into the e-health system that currently used by the healthcare centers.