Objective Earlier studies of eosinophilic granulomatosis with polyangiitis (Churg‐
Strauss)(EGPA), with limited patient numbers and followup durations, demonstrated that
clinical presentation at diagnosis, but not outcome, differed according to antineutrophil
cytoplasmic antibody (ANCA) status. This study was undertaken to describe the main
characteristics of a larger patient cohort and their long‐term outcomes. Methods A
retrospective study of EGPA patients in the French Vasculitis Study Group cohort who …

Eosinophilic granulomatosis with polyangiitis (EGPA), formerly called Churg–Strauss
syndrome, is a systemic necrotizing vasculitis of small-and medium-size vessels,
characterized by asthma and blood eosinophilia. EGPA typically occurs in patients with
preexisting asthma, and involves the skin, lungs, and peripheral nerves. Poor-prognosis
factors (ie, involvement (s) of the gastrointestinal tract, heart, and/or kidney) have been
assessed with the Five-Factor Score (FFS). One-third of the patients have anti …