Epigenetic modifications are involved in global reprogramming of the cell transcriptome.
Therefore, synchronized major shifts in the expression of many genes could be achieved
through epigenetic changes. The regulation of gene expression could be implemented by
different epigenetic events including histone modifications, DNA methylation and chromatin
remodelling. Interestingly, it has been documented that reprogramming of somatic cells to
induced pluripotent stem (iPS) cells is also a typical example of epigenetic modifications …