Epinephrine concentration (1: 100,000 or 1: 200,000) does not affect the clinical efficacy of 4% articaine for lower third molar removal: a double-blind, randomized …

CF Santos, KCS Modena, FPM Giglio, VT Sakai… - Journal of oral and …, 2007 - Elsevier
PURPOSE: This study compared the use of 4% articaine in association with 1: 100,000 (10
μg/mL; A100) or 1: 200,000 (5 μg/mL; A200) epinephrine in lower third molar removal.
PATIENTS AND METHODS: Fifty healthy volunteers underwent removal of symmetrically
positioned lower third molars, in 2 separate appointments, under local anesthesia with either
A100 or A200, in a double-blind, randomized, and crossed manner. Latency, duration of
postoperative analgesia, duration of anesthetic action on soft tissues, intraoperative …
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