antiphospholipid syndrome (APS) during a 5-year period and to determine clinical and
immunological parameters with prognostic significance. METHODS: The clinical and
immunological features of a cohort of 1000 patients with APS from 13 European countries
who had been followed up from 1999 to 2004 were analysed. RESULTS: 200 (20%) patients
developed APS-related manifestations during the 5-year study period. Recurrent thrombotic …